For three years, seventeen-year-old Cas Lowood has carried on his father's work of dispatching the murderous dead, traveling with his kitchen-witch mother and their spirit-sniffing cat, but everything changes when he meets Anna, a girl unlike any ghost he has faced before.
When fifteen-year-old Lexi's younger sister Kasey begins behaving strangely and their old Victorian house seems to take on a life of its own, Lexi investigates and discovers some frightening facts about previous occupants of the house, leading her to believe that many lives are in danger.
In a small South Carolina town, where it seems little has changed since the Civil War, sixteen-year-old Ethan is powerfully drawn to Lena, a new classmate with whom he shares a psychic connection and whose family hides a dark secret that may be revealed on her sixteenth birthday.
When he and his mother move into an old farmhouse in the English countryside, asthmatic, twelve-year-old Jack discovers that he can communicate with the ghosts inhabiting the house and inadvertently establishes a relationship with a tormented, malevolent spirit that threatens to destroy both his mother and himself.
While dealing with her first boyfriend and suddenly being pressed into service as a substitute cheerleader, seventeen-year-old Daisy Giordano, daughter and sister of psychics but herself a "normal," attempts to help her mother discover who is behind a series of bizarre attacks on teenage girls in their little town of Nightshade, California.